Ionic currents in single ureter smooth muscle cell
نویسندگان
چکیده
منابع مشابه
Ureter Smooth Muscle Cell Orientation in Rat Is Predominantly Longitudinal
In ureter peristalsis, the orientation of the contracting smooth muscle cells is essential, yet current descriptions of orientation and composition of the smooth muscle layer in human as well as in rat ureter are inconsistent. The present study aims to improve quantification of smooth muscle orientation in rat ureters as a basis for mechanistic understanding of peristalsis. A crucial step in ou...
متن کاملWhole-cell and single-channel calcium currents of isolated smooth muscle cells from saphenous vein.
Whole-cell and single-channel calcium currents in enzymatically isolated dog saphenous vein cells were recorded by the patch-clamp method. Test pulses to negative potentials from holding potentials of -90 to -40 mV elicited currents that inactivated quickly and in a voltage-dependent manner (called I low for low threshold). A second calcium current persisted even at relatively positive holding ...
متن کاملA-type potassium currents in smooth muscle.
A-type currents are voltage-gated, calcium-independent potassium (Kv) currents that undergo rapid activation and inactivation. Commonly associated with neuronal and cardiac cell-types, A-type currents have also been identified and characterized in vascular, genitourinary, and gastrointestinal smooth muscle cells. This review examines the molecular identity, biophysical properties, pharmacology,...
متن کاملNa(+)-Ca++ exchange mechanism in smooth muscle of the ureter.
The participation of Na+ in regulation of intracellular Ca++ content and in formation of spontaneous action potentials of guinea-pig ureter was studied. It was shown that the fast decrease of intracellular Ca++ in the Ca(++)-loaded muscles was accompanied by enhancement of Na+ content in the cells. The concentration gradient of Na+ was found to define the effectiveness of Ca(++)-extrusion from ...
متن کاملIonic Currents during Hypoxia in Voltage- Clamped Cat Ventricular Muscle
Neer EJ (1973) The vasopressin-sensitive adenylate cyclase of the rat medulla. J Biol Chem 248: 4775-4781 Rona G, Chappel CI, Balazo T, Gaudry R (1959) An infarct-like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat. Arch Pathol 67: 443-455 Sayers G, Beall RJ, Seelig S (1972) Isolated adrenal cells: Adenocorticotrophic hormone, calcium, steroidogenesis, and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1988
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)57330-9